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A renal transplant recipient enjoys a grapefruit for breakfast. He is taking cyclosporine (Sandimmune). The nurse should instruct him that ingestion of grapefruit would have which of the following effects?

1. Cause an increase in edema and renal insufficiency.
2. Increase the serum level of cyclosporine.
3. Assist in relieving his constipation.
4. Increase renal metabolism of cyclosporine.


The only food interaction of significance with cyclosporine (Sandimmune) is grapefruit. This combination will result in an increased serum cyclosporine level. The other options are completely false. The only correct statement is answer 2. In selecting the correct answer, recall the contraindications when taking the medication.


Member since: April 2011
(Boynton Beach,FL) Original question source

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Topics: Adult Health: Immunological, Nursing Process: Implementation

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